IMTEC-SS-A/Ro-Antibodies Rheumatism Autoimmune Diagnostics IMTEC Selangor, Malaysia, Kuala Lumpur (KL), Rawang Supplier, Suppliers, Supply, Supplies | Medic SC Sdn Bhd
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  • IMTEC-SS-A/Ro-Antibodies is an indirect solid-phase enzyme immunoassay (ELISA) for quantitative and qualitative measurement of IgG class autoantibodies against SS-A in human serum. The assay is intended for in vitro diagnostic use only as an aid in the diagnosis of Sjögren’s syndrome.

  • Autoantibodies directed to Ro52 and Ro60 are highly specific for Sjögren's syndrome (SS) and for systemic lupus erythematosus (SLE) respectively. In over 60% of primary SS (pSS) anti-Ro52-antibodies are occurring isolated (only 5% in SLE). An isolated occurrence of anti-Ro60 antibodies was observed in 11% of SLE but none in pSS. If anti-Ro60 antibodies are positive but anti-SS/B-La antibodies negative, a development of nephritis is significantly more likely than in other patients with SLE. Anti-SS-A/Ro antibodies have been detected in nearly 100% of newborns with neonatal lupus erythematosus (NLE). There is a strong correlation between positive test results for anti-SS-A/Ro antibodies and the occurrence of a congenital heart block.

  • Code ITC70026  96Tests

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